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KMID : 0356919920250061195
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Korean Journal of Anesthesiology
1992 Volume.25 No. 6 p.1195 ~ p.1199
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The Preventive Effect of Propofol on Postoperative Nausea and Vomiting after Strabismus Surgery in Pediatric Patients
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Abstract
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Nausea and vomiting are common problems after strabismus surgery in pediatric patients. We compared the effect of propofol with N2O with the effect of a conventional regimen consisting of halothane -N2O on the occurrence of oculocardiac
reflex(OCR),
recovery characteristics and the incidence of postoperative emesis after strabismus surgery in 46 ASA physical status I children. After intravenous injection of atropine(0.02mg/kg), patients were randomly assigned to one of two groups. Group
1(conrol)
received thiopental, vecuronum, halothane and N2O; Group 2(study), propofol 2 mg/kg and vecuronium bolus followed by infusion of propofol 160mg/kg/min.
Patients in group 2 had more episodes of OCR response than group 1, but had shorter time to recovery from anesthesia(p<0.05). But there was no significant difference in the incidence of postoperative nausea and vomiting between two groups . We
conclude
that the sufficient doses of propofol only regimen and atropine preadministration(0.02mg/kg) will be necessary in the strabismus surgery of children for the purposes of the prevention of intraoperative OCR, rapid recovery from anesthesia and
reduction
of postoperative emesis.
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